Year 2017, Volume 4 , Issue 2, Pages 114 - 122 2017-04-23

Total Phenolics, Antioxidant, Antibacterial and Cytotoxic Activity Studies of Ethanolic Extracts Arisarum vulgare O.Targ.Tozz. and Dracunculus vulgaris Schott.

Çiğdem AYDIN [1] , Cennet ÖZAY [2] , Olcay DÜŞEN [3] , Ramazan MAMMADOV [4] , Figen ORHAN [5]


The present study reports the antioxidant, total phenolics, antibacterial and cytotoxic activities of Arisarum vulgare and Dracunculus vulgaris of aerial and under ground ethanol extracts.  The antioxidant activity was determined by DPPH radical scavenging activity and β-carotene linoleic acid assays. Folin-Ciocalteu assay was used to detect total phenolic contents in the extract. In vitro cytotoxic activity was determined by the Brine shrimp lethality test. Antibacterial activity was investigated with the microdilution method. As a result, under ground parts of the extract showed higher antioxidant activity than aerial parts of the extract. Total phenolics ranged from 14.5±2.02 to 53.4±2.01 mg GAE/g, and the antioxidant activity according to the β-carotene/linoleic acid assay ranged from 70.76±1.08 % to 85.43±1.05 and according to the DPPH assay IC50 values ranged from 0.089±1.02 to 1.095±1.07mg/ml. The A. vulgare under ground extract was tested against 2 and showed a good antibacterial activity at a concentration of <50 mg/mL Minimum inhibitory concentration (MIC) values for the bacteria S.aureus. The results of the cytotoxic activities showed a very high activity of the extracts, D.vulgaris under ground extract  (LC50 = 10.6 µg/mL).

Antioxidant, antibacterial, cytotoxic, Arisarum vulgare, Dracunculus vulgaris
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Subjects Biology
Published Date July
Journal Section Articles
Authors

Author: Çiğdem AYDIN

Author: Cennet ÖZAY

Author: Olcay DÜŞEN
Institution: PAMUKKALE ÜNİVERSİTESİ
Country: Turkey


Author: Ramazan MAMMADOV
Institution: PAMUKKALE ÜNİVERSİTESİ
Country: Turkey


Author: Figen ORHAN

Dates

Publication Date : April 23, 2017

Bibtex @research article { ijsm307944, journal = {International Journal of Secondary Metabolite}, issn = {}, eissn = {2148-6905}, address = {Prof. Dr. İzzet KARA}, publisher = {İzzet KARA}, year = {2017}, volume = {4}, pages = {114 - 122}, doi = {10.21448/ijsm.307944}, title = {Total Phenolics, Antioxidant, Antibacterial and Cytotoxic Activity Studies of Ethanolic Extracts Arisarum vulgare O.Targ.Tozz. and Dracunculus vulgaris Schott.}, key = {cite}, author = {AYDIN, Çiğdem and ÖZAY, Cennet and DÜŞEN, Olcay and MAMMADOV, Ramazan and ORHAN, Figen} }
APA AYDIN, Ç , ÖZAY, C , DÜŞEN, O , MAMMADOV, R , ORHAN, F . (2017). Total Phenolics, Antioxidant, Antibacterial and Cytotoxic Activity Studies of Ethanolic Extracts Arisarum vulgare O.Targ.Tozz. and Dracunculus vulgaris Schott.. International Journal of Secondary Metabolite , 4 (2) , 114-122 . DOI: 10.21448/ijsm.307944
MLA AYDIN, Ç , ÖZAY, C , DÜŞEN, O , MAMMADOV, R , ORHAN, F . "Total Phenolics, Antioxidant, Antibacterial and Cytotoxic Activity Studies of Ethanolic Extracts Arisarum vulgare O.Targ.Tozz. and Dracunculus vulgaris Schott.". International Journal of Secondary Metabolite 4 (2017 ): 114-122 <http://ijsm.ijate.net/en/issue/27381/307944>
Chicago AYDIN, Ç , ÖZAY, C , DÜŞEN, O , MAMMADOV, R , ORHAN, F . "Total Phenolics, Antioxidant, Antibacterial and Cytotoxic Activity Studies of Ethanolic Extracts Arisarum vulgare O.Targ.Tozz. and Dracunculus vulgaris Schott.". International Journal of Secondary Metabolite 4 (2017 ): 114-122
RIS TY - JOUR T1 - Total Phenolics, Antioxidant, Antibacterial and Cytotoxic Activity Studies of Ethanolic Extracts Arisarum vulgare O.Targ.Tozz. and Dracunculus vulgaris Schott. AU - Çiğdem AYDIN , Cennet ÖZAY , Olcay DÜŞEN , Ramazan MAMMADOV , Figen ORHAN Y1 - 2017 PY - 2017 N1 - doi: 10.21448/ijsm.307944 DO - 10.21448/ijsm.307944 T2 - International Journal of Secondary Metabolite JF - Journal JO - JOR SP - 114 EP - 122 VL - 4 IS - 2 SN - -2148-6905 M3 - doi: 10.21448/ijsm.307944 UR - https://doi.org/10.21448/ijsm.307944 Y2 - 2017 ER -
EndNote %0 International Journal of Secondary Metabolite Total Phenolics, Antioxidant, Antibacterial and Cytotoxic Activity Studies of Ethanolic Extracts Arisarum vulgare O.Targ.Tozz. and Dracunculus vulgaris Schott. %A Çiğdem AYDIN , Cennet ÖZAY , Olcay DÜŞEN , Ramazan MAMMADOV , Figen ORHAN %T Total Phenolics, Antioxidant, Antibacterial and Cytotoxic Activity Studies of Ethanolic Extracts Arisarum vulgare O.Targ.Tozz. and Dracunculus vulgaris Schott. %D 2017 %J International Journal of Secondary Metabolite %P -2148-6905 %V 4 %N 2 %R doi: 10.21448/ijsm.307944 %U 10.21448/ijsm.307944
ISNAD AYDIN, Çiğdem , ÖZAY, Cennet , DÜŞEN, Olcay , MAMMADOV, Ramazan , ORHAN, Figen . "Total Phenolics, Antioxidant, Antibacterial and Cytotoxic Activity Studies of Ethanolic Extracts Arisarum vulgare O.Targ.Tozz. and Dracunculus vulgaris Schott.". International Journal of Secondary Metabolite 4 / 2 (April 2017): 114-122 . https://doi.org/10.21448/ijsm.307944
AMA AYDIN Ç , ÖZAY C , DÜŞEN O , MAMMADOV R , ORHAN F . Total Phenolics, Antioxidant, Antibacterial and Cytotoxic Activity Studies of Ethanolic Extracts Arisarum vulgare O.Targ.Tozz. and Dracunculus vulgaris Schott.. IJSM. 2017; 4(2): 114-122.
Vancouver AYDIN Ç , ÖZAY C , DÜŞEN O , MAMMADOV R , ORHAN F . Total Phenolics, Antioxidant, Antibacterial and Cytotoxic Activity Studies of Ethanolic Extracts Arisarum vulgare O.Targ.Tozz. and Dracunculus vulgaris Schott.. International Journal of Secondary Metabolite. 2017; 4(2): 122-114.