Year 2019, Volume 6, Issue 2, Pages 172 - 195 2019-08-07

Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review

Abeer Kazmi [1] , Mubarak Ali Khan [2] , Huma Ali [3]

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Medicinal and aromatic plants and their refined natural products have gained global attraction for their therapeutic potential against many human diseases. Nigella sativa is a medicinally important plant, commonly known as Black cumin or Black seed is a dicotyledon plant of the Ranunculaceae family. It is in common use for a longer time in history as preservative and spice and has also been extensively utilized by different communities around the globe. Black cumin has been an eminent component of traditional medicine systems like Unani and Tibb, Ayurveda and Siddha. Its biological activities include antidiarrheal, analgesic, antibacterial, liver tonic, diurectic, digestive agent and to treat several skin disorders. Furthermore, the therapeutic properties also include antidiabetic, anticancer, antihypertensive, anti-inflammatory, hepatoprotective, spasmolytic and bronchodialator. This is all because of its miraculous healing power that it has been ranked as top ranked, among evidence based herbal medicines. The literature supports that the pharmacological activities of Nigella sativa are mainly because of the essential oil and its constituents particularly thymoquinone. The current review is an attempt to present a detailed literature survey regarding chemical composition, phytochemistry, therapeutic potential and biotechnological approaches to enhance the medicinal potential of this valuable plant.
Chemical composition, Medicinal significance, Nigella Sativa, Black cumin, Phytochemistry, Therapeutic potential, Biotechnological approaches
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Primary Language en
Subjects Biology
Published Date June
Journal Section Articles
Authors

Author: Abeer Kazmi
Institution: Bacha Khan University
Country: Pakistan


Orcid: 0000-0002-7994-4244
Author: Mubarak Ali Khan (Primary Author)
Institution: Abdul Wali Khan University Mardan
Country: Pakistan


Author: Huma Ali
Institution: Capital University of Science and Technology
Country: Pakistan


Bibtex @review { ijsm575075, journal = {International Journal of Secondary Metabolite}, issn = {}, eissn = {2148-6905}, address = {İzzet KARA}, year = {2019}, volume = {6}, pages = {172 - 195}, doi = {10.21448/ijsm.575075}, title = {Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review}, key = {cite}, author = {Kazmi, Abeer and Khan, Mubarak Ali and Ali, Huma} }
APA Kazmi, A , Khan, M , Ali, H . (2019). Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review. International Journal of Secondary Metabolite, 6 (2), 172-195. DOI: 10.21448/ijsm.575075
MLA Kazmi, A , Khan, M , Ali, H . "Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review". International Journal of Secondary Metabolite 6 (2019): 172-195 <http://ijsm.ijate.net/issue/44217/575075>
Chicago Kazmi, A , Khan, M , Ali, H . "Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review". International Journal of Secondary Metabolite 6 (2019): 172-195
RIS TY - JOUR T1 - Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review AU - Abeer Kazmi , Mubarak Ali Khan , Huma Ali Y1 - 2019 PY - 2019 N1 - doi: 10.21448/ijsm.575075 DO - 10.21448/ijsm.575075 T2 - International Journal of Secondary Metabolite JF - Journal JO - JOR SP - 172 EP - 195 VL - 6 IS - 2 SN - -2148-6905 M3 - doi: 10.21448/ijsm.575075 UR - https://doi.org/10.21448/ijsm.575075 Y2 - 2019 ER -
EndNote %0 International Journal of Secondary Metabolite Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review %A Abeer Kazmi , Mubarak Ali Khan , Huma Ali %T Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review %D 2019 %J International Journal of Secondary Metabolite %P -2148-6905 %V 6 %N 2 %R doi: 10.21448/ijsm.575075 %U 10.21448/ijsm.575075
ISNAD Kazmi, Abeer , Khan, Mubarak Ali , Ali, Huma . "Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review". International Journal of Secondary Metabolite 6 / 2 (August 2019): 172-195. https://doi.org/10.21448/ijsm.575075